Back to search results

Risk Assessment for Stomach Cancer

This study is looking at different ways to identify people at high risk for stomach cancer. Researchers are testing the usefulness of questionnaires, blood samples, a breath test for a bacteria called *H. pylori* (which can cause stomach inflammation and ulcers), and endoscopies (a procedure where a thin, flexible tube with a camera is used to look inside your esophagus, stomach, and small intestine). The goal is to see if these tests can effectively find people who might be more likely to develop stomach cancer. You may be able to join if you are between 40 and 80 years old and identify as Asian, Hispanic, or Black American.

Study design
This interventional study plans to enroll 240 participants. It aims to see how well community outreach and clinical assessments can find people at high risk for stomach cancer.
What's involved
You would complete questionnaires, provide blood samples, and undergo an *H. pylori* breath test. If you are identified as high-risk, you may also have an endoscopy with a possible biopsy. You will complete questionnaires annually for up to 3 years.
Compensation
Not stated in the trial record.
Follow-up
Participants are followed up annually for a total of 3 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06408220

Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer

Recruiting
NAAges 40–80InterventionalScreening
City of Hope Medical Center
~240 participants
Updated 2026-03-13 on ClinicalTrials.gov
What's tested:BiopsyBiospecimen CollectionBreath TestEsophagogastroduodenoscopyQuestionnaire Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of screening individuals found to be at high risk for gastric cancer (feasibility)
Measured over At time of screening up to 3 years

Conditions

Gastric Carcinoma

Explore related trials

Gastric Carcinoma

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Yanghee Woo · PRINCIPAL_INVESTIGATOR · City of Hope Medical Center

Who to contact

Yanghee Woo
[email protected]
626-218-0220
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Documented informed consent of the participant and/or legally authorized representative
Assent, when appropriate, will be obtained per institutional guidelines
Age: ≥ 40 years to ≤ 80 years
Identify as a racial minority either Asian, Hispanic, or Black American
Willingness to:
Provide blood samples and undergo upper endoscopy

Exclusion

Identify as Non-Hispanic White
History of gastric cancer
Known premalignant lesions of the stomach
History of upper endoscopy within 2 years
Women of childbearing potential: Pregnant/ nursing
An employee who is under the direct/indirect supervision of the principal investigator (PI)/a coinvestigator/the study manager
A direct study team member

What this trial measures

  • Percentage of screening individuals found to be at high risk for gastric cancer (feasibility)At time of screening up to 3 years

    Study feasibility will be defined as ≥ 10% of screened individuals found to be at high risk for gastric cancer. The study will be successful if ≥ 10% of screened individuals (24 of ≤ 240) have a risk score of ≥ 12 or have signs/symptoms that have persisted for ≥ 1 month that are associated with gastric cancer. The reported results will include counts/proportions of screened individuals found to be at high risk for gastric cancer (≥ 12 risk score).