CBD for Knee Osteoarthritis
This study is looking at whether Cannabidiol (CBD) Extract can help people with knee osteoarthritis (a common joint disease causing pain and disability). Researchers want to see if CBD Extract is safe, acceptable, and helps reduce knee pain. You might be able to join if you are between 40 and 75 years old, have a diagnosis of knee osteoarthritis, and experience moderate to severe knee pain. The study will compare CBD Extract to a placebo (an inactive substance that looks like the real treatment). Researchers will measure your pain levels and how you feel about the treatment over one month to see if CBD Extract is helpful. The current status of this study is unclear.
- Study design
- This interventional study plans to enroll 30 participants. It compares Cannabidiol (CBD) Extract to a placebo.
- What's involved
- You would take either Cannabidiol (CBD) Extract or a placebo three times daily with food, administered under the tongue. You would report on adverse events weekly for one month, and complete questionnaires and self-report pain ratings at the beginning and end of the month, and daily for one month.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain and acceptability of treatment will be measured at baseline and one month, and adverse events will be monitored weekly for one month.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
CBD for Knee Osteoarthritis
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)Weekly until 1 month
Categorical scale, None or not at all (0) and very severe or very much (4), higher scores mean worse outcome
- Theoretical Framework of Acceptability Questionnaire (TFAQ)Baseline and 1 month
Likert scale, 1 and 5, higher scores mean worse outcome
- Self-report Ratings of Knee PainBaseline and 1 month, daily until 1 month
Numeric Rating Scale, 0 and 10, higher scores mean worse outcome
- Physical ActivityDaily until 1 month
Accelerometer measures step counts per day
- Western Ontario and McMaster Universities Arthritis Index (WOMAC)Baseline and 1 month
Categorical scale, none (0) and extreme (4), higher scores mean worse outcome