This study is looking at a new way to help doctors decide if critically ill patients in the ICU (Intensive Care Unit) need more fluids. Giving too much fluid can be harmful, so it's important to know who will benefit. Researchers are using a method called VTI (Velocity Time Integral), which is a measurement from an echocardiogram (a heart ultrasound), along with Trendelenburg positioning (tilting the patient with their head down). They will compare a patient's VTI measurement when lying flat to when they are in the Trendelenburg position. The goal is to find a specific change in VTI that can accurately predict if a patient will respond well to fluid therapy, helping to prevent complications like fluid overload. This study plans to enroll 400 adult ICU patients who might need fluids due to low blood pressure, fast heart rate, or high lactate levels. The study status is currently unclear.

Study design

This interventional study involves comparing each patient to themselves, with 400 planned participants. Patients will undergo echocardiograms in two different positions.

What's involved

You would have an echocardiogram performed while lying flat and then again while in the Trendelenburg position, for research purposes.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome, change in VTI cutoff, will be measured at approximately 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.