Prosthetic Performance Enhancement Trial for Lower Limb Amputation

This study, called the Prosthetic Performance Enhancement Trial, is for people with a lower limb amputation (at the ankle, below the knee, or above the knee) who use a walking prosthesis. It aims to see if a walking program on uneven surfaces can help improve walking skills and confidence. You would be randomly assigned to either walk on a flat surface or an uneven surface. The training involves walking for up to 2 minutes at a time, with breaks, three times a week for four weeks. The main goal of this pilot study is to see how well people stick to the training and to improve the training plans for future research. You must be at least 18 years old, use your prosthesis regularly, have a good socket fit, and be able to walk for three minutes.

Study design
This is an interventional study with a planned enrollment of 35 participants. You would be randomly assigned to one of two training groups: flat terrain or uneven terrain.
What's involved
You would participate in walking practice three times a week for four weeks. Each session involves up to 12 sets of 2-minute continuous walking with rest breaks.
Compensation
Not stated in the trial record.
Follow-up
Your adherence to the training will be measured over the 4 weeks of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06419920

Prosthetic Performance Enhancement Trial

Recruiting
NAAges 18+Interventional
University of Nevada, Las Vegas
~35 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:Flat terrain locomotor trainingUneven terrain locomotor training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Session adherence
Measured over Through study completion, over 4 weeks
Amputation
Lower Limb Amputation Below Knee (Injury)
Lower Limb Amputation Above Knee (Injury)
Lower Limb Amputation at Ankle (Injury)
Lower Limb Amputation Knee
Lower Limb Amputation at Hip (Injury)

NCT06419920

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Nevada Las Vegas

    Las Vegas, Nevadastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Jenny A Kent, PhD, CSci · PRINCIPAL_INVESTIGATOR · University of Nevada, Las Vegas

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

lower limb amputation at ankle (Symes) level and above
age 18+ years
fitted with a walking prosthesis and use it regularly for home and/or community ambulation
good socket fit, assessed by a score of 8-10 on the socket fit comfort scale
able to walk for three minutes at a time with or without an assistive device

Exclusion

leg/foot ulcer or other conditions that cause pain during weight-bearing
poor skin integrity that could cause tissue breakdown by walking
cardiovascular, respiratory or other critical health conditions that preclude moderate physical activity
unilateral or bilateral upper limb absence or loss at the wrist and above that precludes use of handrails bilaterally, or would require asymmetrical adaptation to body posture for use.
pregnancy
  • Session adherenceThrough study completion, over 4 weeks

    Percentage of planned sessions attended, per participant.