Genetic Testing Access for Underserved Cancer Patients

This study aims to improve access to genetic testing for people with certain cancers, especially those from minority groups or rural areas who may have limited access to genetic counseling. It compares two ways of providing information about genetic testing: through a computer-generated character called PERLA, or through a human genetics healthcare provider. The study wants to see if PERLA can help more patients get genetic testing within three months of starting their cancer care. You may be able to join if you are over 18 and have breast cancer (including male breast cancer, triple-negative, or diagnosed before age 50), ovarian cancer, pancreatic cancer, or metastatic (spread to other parts of the body) or high-risk prostate cancer.

Study design
This interventional study plans to enroll 800 participants. It compares receiving genetic counseling from a provider to receiving genetics education through an educational intervention.
What's involved
You may participate in focus groups, usability testing with interviews, or be randomized to receive either provider-based genetic counseling or genetics education.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, genetic testing, is measured up to 3 months after starting the study.

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NCT06422455

Access to Genetic Testing in Underserved Patients With Cancer

Recruiting
NAAges 18+InterventionalHealth services
University of Southern California
~800 participants
Updated 2026-03-18 on ClinicalTrials.gov
What's tested:Best PracticeEducational InterventionElectronic Health Record ReviewGenetic CounselingInterviewSurvey Administration

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of participants who receive genetic testing
Measured over Up to 3 months
Breast Carcinoma
Male Breast Carcinoma
Malignant Solid Neoplasm
Metastatic Prostate Carcinoma
Ovarian Carcinoma
Pancreatic Exocrine Neoplasm
Stage IVB Prostate Cancer American Joint Committee on Cancer v8
Triple-Negative Breast Carcinoma
2 sites across 2 states
California1
New York1
  • Charite Ricker, MS · PRINCIPAL_INVESTIGATOR · University of Southern California

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Eligibility criteria

Inclusion

Age \> 18 years old
Diagnosed with least one of the following:
Epithelial ovarian cancer
Exocrine pancreatic cancer
Metastatic or high or very high-risk prostate cancer
Breast cancer at or before age 50
Bilateral breast cancer
Triple negative breast cancer
Male breast cancer OR
Healthcare provider who treats patients with any of the above types of cancer
Able to read and write in English or Spanish
Able to provide informed consent
Patients with none of the listed cancer diagnoses and clinical characteristics
Healthcare provider who do not treats cancer patients

Exclusion

Patients who cannot provide informed consent
Patients who cannot see, read, or write
  • Proportion of participants who receive genetic testingUp to 3 months

    The proportion of participants who receive genetic testing will be reported.