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Digital Health App for Advanced Lung Cancer

This study is testing a digital health app called THRIVE to see if it can improve the quality of life and symptoms for people with advanced lung cancer. You might be able to join if you are an adult (18 or older) recently diagnosed with advanced non-small cell lung cancer (NSCLC) or extensive stage small cell lung cancer (SCLC), and your general health and activity level are good (ECOG Performance Status = 0-2). The main goal is to see how your quality of life, measured by the Functional Assessment of Cancer Therapy - Lung (FACT-L) survey, changes after 12 weeks. The current status of this study is unclear, but it plans to enroll 250 participants.

Study design
This is a multi-site randomized controlled trial comparing the THRIVE digital health app to usual care, involving 250 participants.
What's involved
Participants will receive an iPad with the THRIVE app if assigned to that group. You will complete surveys at the beginning, and again at 6, 12, and 24 weeks.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 weeks after enrolling in the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06427954

Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer

Recruiting
NAAges 18+InterventionalSupportive care
Massachusetts General Hospital
~250 participants
Updated 2026-07-13 on ClinicalTrials.gov
What's tested:Digital Health App

At a glance

Recruiting sites
2 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Functional Assessment of Cancer Therapy - Lung (FACT-L)
Measured over 12 weeks

Conditions

Lung Cancer

Explore related trials

Lung Non-Small Cell CarcinomaLung Small Cell Carcinoma

Where it's being run

3 sites across 2 states
California2
Massachusetts1

Who to contact

Jennifer Temel
[email protected]
6177244000
Email the study team

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Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

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Eligibility criteria

Inclusion

Adults (greater than or equal to 18 years)
Diagnosed with advanced non-small cell lung cancer (NSCLC) that is not being treated with curative intent or extensive stage small cell lung cancer (SCLC) within the past 12 weeks.
Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) = 0-2 (i.e., fully active to at least ambulatory and up and about more than 50% of waking hours).
Sufficient English proficiency to utilize THRIVE in English (Note: patients can complete outcome measures in Spanish if preferred).

Exclusion

Significant uncontrolled psychiatric disorder (e.g., psychotic disorder, bipolar disorder, major depression) or other co-morbid disease (e.g., dementia, cognitive impairment), which the treating oncology clinician reports would prohibit the ability to participate in study procedures.

What this trial measures

  • Functional Assessment of Cancer Therapy - Lung (FACT-L)12 weeks

    Quality of Life (higher scores indicate better quality of life)