Exercise Interventions for Metastatic Castrate-Sensitive Prostate Cancer

This study, called Prostate 006, is looking at two different home-based exercise programs for men with newly diagnosed metastatic castrate-sensitive prostate cancer (mCSPC) who are starting ADT (Androgen Deprivation Therapy) or ARSI (Androgen-Receptor Signaling Inhibitors). You would be randomly assigned to either a walking program or a high-intensity interval training (HIIT) cycling program. The main goal is to see how many participants complete their assigned exercise program and how satisfied they are. Researchers also want to learn if these exercises can improve fitness and muscle strength, and if that helps with feeling tired during cancer treatment. The study plans to enroll 24 men aged 18 or older with mCSPC.

Study design
This is an interventional study where 24 participants will be randomly assigned to one of two home-based exercise programs.
What's involved
You will have 1-2 training sessions at UVA, then exercise at home for 12 weeks. You will also complete aerobic and strength tests before and after the program, and answer questionnaires.
Compensation
Not stated in the trial record.
Follow-up
Participants will have a follow-up assessment 14 weeks from the start of the intervention.

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NCT06429813

Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

Recruiting
NAAges 18+InterventionalSupportive care
Paul Viscuse
~24 participants
Updated 2026-05-04 on ClinicalTrials.gov
What's tested:Home-Based Exercise Intervention - WalkingHome-Based Exercise Intervention - HIIT Cycling

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants who complete the post-intervention follow-up assessment
Measured over 14 weeks from the start of the intervention
Castrate Sensitive Prostate Cancer
Metastatic Prostate Cancer
1 sites across 1 states
Virginia1
  • Paul Viscuse, MD · PRINCIPAL_INVESTIGATOR · University of Virginia

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  • Number of participants who complete the post-intervention follow-up assessment14 weeks from the start of the intervention

    Percentage of participants who complete the post-intervention follow-up assessment