NCT06430268

Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants

Enrolling by Invitation
NAAges 18–80InterventionalTreatment
Andrea Ravida
~90 participants
Updated 2026-05-18 on ClinicalTrials.gov
What's tested:implant decontamination with titanium curetteimplant decontamination with Air-Flow device

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of clean implant surface area following implant decontamination approaches
Measured over Right after decontamination and implant removal (T0)
Peri-Implantitis
Dental Implant Failed
1 sites across 1 states
Pennsylvania1
  • Andrea Ravida, DDS MS PhD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Adult individuals between 18 and 80 years of age who require the explantation of at least one titanium or titanium alloy implant due to severe peri-implantitis (\> 50% bone loss and signs of inflammation);
Individuals who did not undergo surgical or non-surgical peri-implant therapy in the previous 6 months.

Exclusion

Acute infection associated with adjacent teeth;
Any technical complication that does not allow implant removal using a reverse torque device;
Active infectious diseases of any kind;
Medical conditions which requires premedication prior to dental treatments/visits;
Pregnant women or planning to become pregnant (self-reported);
History of radiotherapy in the head and neck or chemotherapy in the last 3 years;
Any other diseases or medications that may contraindicate the surgical procedure or compromise wound healing.
  • Percentage of clean implant surface area following implant decontamination approachesRight after decontamination and implant removal (T0)

    The cleaned surface area will be planimetrically recorded, and the percentage presence/absence of mineralized deposits as well as scratches on the decontaminated implant surfaces will be determined with the aid of a stereomicroscope.