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Exercise Prehabilitation for Esophageal Cancer

This study is looking at whether an exercise program, called "prehabilitation," is practical and acceptable for people with esophageal cancer who are preparing for surgery to remove their tumor. The program involves physical activity and resistance training. You might be able to join if you have locoregional esophageal cancer (cancer that hasn't spread far), are generally able to perform daily activities, have a treatment plan that includes chemotherapy, radiation, and surgery, and can read and speak English. The main goal is to see how many people stick with the exercise program for up to 11 weeks. The study plans to enroll 20 participants, but its current recruitment status is unclear.

Study design
This is an interventional study with an enrollment of 20 participants. The study is testing a behavioral intervention (exercise).
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, retention, is measured up to 11 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06430346

Exercise Prehabilitation for Locoregional Esophageal Cancer

Recruiting
NAAges 18+InterventionalSupportive care
H. Lee Moffitt Cancer Center and Research Institute
~20 participants
Updated 2025-12-04 on ClinicalTrials.gov
What's tested:Exercise

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Retention
Measured over Up to 11 weeks

Conditions

Esophageal Cancer

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Esophageal Carcinoma

NCT06430346

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Moffitt Cancer Center

    Tampa, Floridastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Nathan Parker, PhD · PRINCIPAL_INVESTIGATOR · Moffitt Cancer Center

Who to contact

Nathan Parker, PhD
[email protected]
813-745-6849
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Biopsy-proven locoregional esophageal cancer (LEC)
Eastern Cooperative Oncology Group (ECOG) performance status 0-2
Treatment plan including neoadjuvant chemoradiation therapy and surgical resection
Ability to read and speak English

Exclusion

Regular engagement in resistance training (2x/week targeting all major muscle groups)
Screen failure for exercise safety based on PAR-Q
Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
Recent fracture or acute musculoskeletal injury that precludes ability to participate in resistance training safely
Numeric pain rating scale of 7 or more out of 10
Myopathic or rheumatologic disease that impacts physical function

What this trial measures

  • RetentionUp to 11 weeks

    The number of participants who complete T0 and T1 measures.