Observational Study of Polyethylene Wear in Hip Replacements

This observational study is looking at how different types of polyethylene (a plastic material used in hip replacements) wear down over time. Researchers want to compare a newer material, polyethylene containing Vitamin E, to older types of polyethylene to see if it reduces wear. They will do this by analyzing tissue samples collected during revision hip surgery (when a hip replacement needs to be redone). You might be able to join if you are over 20, need revision hip surgery, and had your first hip replacement at least two years ago. The study aims to find out if the newer material creates fewer or smaller wear particles, which could lead to better long-term outcomes for patients. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll 90 participants. It compares three groups of patients who have had different types of polyethylene in their initial hip replacement.
What's involved
If you participate, tissue samples will be collected during your revision hip arthroplasty (surgery to replace a worn-out hip implant). This tissue is usually discarded during surgery.
Compensation
Not stated in the trial record.
Follow-up
The study measures outcomes when the tissue sample is collected during revision surgery, so there is no specified follow-up period after that.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06432543

Polyethylene Wear Particle Analysis of THA

Recruiting
Not specifiedAges 20+Observational
Osaka Metropolitan University
~90 participants
Updated 2025-01-20 on ClinicalTrials.gov
What's tested:polyethylene

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of polyethylene wear particles
Measured over When tissue sample was collected during THA revision surgery
+3 more outcomes measured
Wear of Articular Bearing Surface of Prosthetic Joint
Hip Arthropathy

NCT06432543

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Mayo Clinic

    Rochester, Minnesotastudy coordinator listed

    Not yet recruiting

  • Osaka Metropolitan University

    Osaka, Japanno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Yukihide Minoda, MD, PhD · PRINCIPAL_INVESTIGATOR · Osaka Metropolitan University

Opens a ready-to-send draft in your own email app — review before sending.

  • Number of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery

    counts / g (tissue sample)

  • Equivalent circle diameter of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery

    equivalent circle diameter \[㎛\]

  • Aspect ratio of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery

    aspect ratio

  • Roundness of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery

    roundness