Observational Study of Polyethylene Wear in Hip Replacements
This observational study is looking at how different types of polyethylene (a plastic material used in hip replacements) wear down over time. Researchers want to compare a newer material, polyethylene containing Vitamin E, to older types of polyethylene to see if it reduces wear. They will do this by analyzing tissue samples collected during revision hip surgery (when a hip replacement needs to be redone). You might be able to join if you are over 20, need revision hip surgery, and had your first hip replacement at least two years ago. The study aims to find out if the newer material creates fewer or smaller wear particles, which could lead to better long-term outcomes for patients. The current recruitment status is unclear.
- Study design
- This is an observational study planning to enroll 90 participants. It compares three groups of patients who have had different types of polyethylene in their initial hip replacement.
- What's involved
- If you participate, tissue samples will be collected during your revision hip arthroplasty (surgery to replace a worn-out hip implant). This tissue is usually discarded during surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study measures outcomes when the tissue sample is collected during revision surgery, so there is no specified follow-up period after that.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Polyethylene Wear Particle Analysis of THA
At a glance
Conditions
NCT06432543
Where you'd take part
This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Mayo Clinic
Rochester, Minnesotastudy coordinator listed
Not yet recruiting
Osaka Metropolitan University
Osaka, Japanno site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Yukihide Minoda, MD, PhD · PRINCIPAL_INVESTIGATOR · Osaka Metropolitan University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery
counts / g (tissue sample)
- Equivalent circle diameter of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery
equivalent circle diameter \[㎛\]
- Aspect ratio of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery
aspect ratio
- Roundness of polyethylene wear particlesWhen tissue sample was collected during THA revision surgery
roundness