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Lean Beef Consumption and Cardiometabolic Health Study

This study is looking at how eating different types of lean beef or plant-based meat affects your heart health and gut bacteria. Researchers want to see if consuming Lean Grass-Fed Beef, Lean Grain-Fed Beef, or Plant-Based Meat changes things like your LDL-C (a type of cholesterol), Interleukin-6 (a marker of inflammation), and the diversity of bacteria in your gut. You might be able to join if you are between 18 and 45 years old, have a BMI between 18-35, and are willing to eat the study foods. The study is currently unclear on its recruitment status.

Study design
This is a 6-week randomized, controlled study with three groups of participants. It plans to enroll 90 people.
What's involved
You would consume either lean grain-fed beef, lean grass-fed beef, or plant-based meat for 6 weeks. Measurements will be taken at the beginning and at week 6.
Compensation
Not stated in the trial record.
Follow-up
Measurements are taken at the beginning and at week 6, which is the end of the intervention period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06433115

Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome

Recruiting
NAAges 18–45InterventionalTreatment
University of Missouri-Columbia
~90 participants
Updated 2025-08-01 on ClinicalTrials.gov
What's tested:Lean (≥90%) Grass-Fed BeefLean (≥90%) Grain-Fed BeefPlant-Based Meat

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
LDL-C concentrations
Measured over Baseline, week 6
+2 more outcomes measured

Conditions

Diet Intervention

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NCT06433115

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Missouri-Columbia

    Columbia, Missouristudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jaapna Dhillon, PhD · PRINCIPAL_INVESTIGATOR · University of Missouri-Columbia

Who to contact

Jaapna Dhillon
[email protected]
573-884-2103
Email the study team

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Eligibility criteria

Inclusion

Age: 18-45 years of age
BMI: 18-35 kg/m2
Willingness to consume study foods.
Willing to comply with study protocol.
Consistent diet and activity patterns for 4 weeks
Weight stable (≤5 kg change over the last 3 months)
Non-smoker \>1 year or more

Exclusion

Allergies to foods provided in the study
Diabetes
Gastrointestinal disease and/or bariatric surgery
Uncontrolled hypertension and blood pressure ≥ 180/110
Illicit drug use
Recent consumption of antibiotics or probiotics
Recent start of medications that affect metabolism or appetite.
Recent blood donation
Drug therapy for coronary artery disease, peripheral artery disease, congestive - heart failure, or dyslipidemia
Pregnant or lactating individuals
Taste or smell disorders
High consumers of red meat or plant-based meat (≥ 4 times/week)

What this trial measures

  • LDL-C concentrationsBaseline, week 6

    Lipid profile

  • Interleukin-6 concentrationsBaseline, week 6

    Inflammatory marker

  • Gut microbial alpha-diversityBaseline, week 6

    Assessed via16S rRNA sequencing