NCT06434168

Impact of Yoga on Cognitive Function

Enrolling by Invitation
NAAges 55–70InterventionalPrevention
Auburn University
~24 participants
Updated 2026-04-06 on ClinicalTrials.gov
What's tested:Yoga interventionControl condition

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Brain structure
Measured over Change from 0-12 weeks, from baseline pre-intervention to 12 weeks post-intervention
+3 more outcomes measured
Heart Failure
Mild Cognitive Impairment
1 sites across 1 states
Alabama1

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Aged 55 years and older
Confirmed heart failure diagnosis with mild cognitive impairment
New York Heart Association functional class II-IV

Exclusion

Co-existing neurological disorders, traumatic brain injury, psychiatric disorders, or terminal illnesses
Have implanted defibrillator, left ventricular assist device placement or cardiac transplant
Have any other implanted metals that interfere with the MRI magnetic field for patient safety
Substance abuse
Pregnant
Unable to perform yoga due to physical limitations or severity of illness
  • Brain structureChange from 0-12 weeks, from baseline pre-intervention to 12 weeks post-intervention

    Using structural magnetic resonance imaging to examine brain structure between intervention and control groups. Less brain alteration is optimal.

  • Brain functional connectivityChange from 0-12 weeks, from baseline pre-intervention to 12 weeks post-intervention

    Functional magnetic resonance imaging is used to examine functional connectivity between intervention and control groups. A balance of activity across different brain regions is optimal.

  • Cognitive functionChange from 0-12 weeks, from baseline pre-intervention to 12 weeks post-intervention

    Using cognitive tests to examine cognitive function and performance between intervention and control groups. A higher score on cognitive tests indicates better cognitive function.

  • Serum brain-derived neurotrophic factorChange from 0-12 weeks, from baseline pre-intervention to 12 weeks post-intervention

    A blood sample will be obtained using phlebotomy to measure the levels of serum brain-derived neurotrophic factor and reported in pg/mL. Higher concentrations are optimal.