Evaluating an Embodied Conversational Agent for Medical Explanations

This study is testing a computer-animated character, called an Embodied Conversational Agent (ECA), that explains medical illustrations. We want to see if using this character helps people understand medical information better and feel less anxious compared to reading documents on their own. We're also comparing the ECA on a regular computer screen to one in immersive virtual reality. You might be able to join if you are over 18, speak English or Spanish fluently, can give your own consent, and have good enough vision to read documents. The study aims to find out which method leads to the best understanding and lowest anxiety. The current recruitment status is unclear.

Study design
This is an interventional study with 300 planned participants. It is a 3-arm randomized experiment, meaning participants will be randomly assigned to one of three groups.
What's involved
Participants will read a patient education document with medical illustrations. Your knowledge and anxiety will be measured at the start and again 30 minutes later.
Compensation
Not stated in the trial record.
Follow-up
Your knowledge and anxiety will be measured at 30 minutes after the intervention.

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NCT06435819

ECA-enhanced Document Explanation RCT

Recruiting
NAAges 18+Interventional
Northeastern University
~300 participants
Updated 2025-10-03 on ClinicalTrials.gov
What's tested:Embodied Conversational Agent (ECA)

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Knowledge
Measured over Baseline and 30 minutes
+1 more outcome measured
Healthy
2 sites across 1 states
Massachusetts2
  • Timothy Bickmore, PhD · PRINCIPAL_INVESTIGATOR · Northeastern University

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Over 18 years old
Speaks English or Spanish fluently
Is able to independently consent
Has adequate corrected vision to read patient education documents
  • KnowledgeBaseline and 30 minutes

    A multiple-item knowledge test designed to test comprehension of the patient education document

  • State Anxiety scale from State-Trait Anxiety Inventory30 minutes

    Self-report state anxiety scale from the State-Trait Anxiety Inventory. 20 items, 4-point Likert scale. A higher score indicates more severe anxiety with a potential range from 20 to 80.