Observational Study of High-Volume Watchman Device Implants

This study, called SAFE HV, is looking at the safety and effectiveness of the Watchman FLX™ or Watchman FLX Pro™ device when many implants are done by one doctor on the same day. The Watchman device is placed in the left atrial appendage (a small pouch in the heart) to prevent blood clots from forming and causing a stroke in people with atrial fibrillation (an irregular heartbeat). Researchers want to see if these high-volume procedures are as safe and effective as those done at lower volumes. You could join if you are 18 or older, are getting a Watchman FLX™ or Watchman FLX Pro™ device as part of your care, and are willing to participate in follow-up. The study is currently unclear on its recruitment status.

Study design
This is an observational study involving 678 participants. It is not randomized, meaning participants are not assigned to different treatment groups by chance.
What's involved
You would participate in baseline and follow-up evaluations for the full length of the study. This includes monitoring for complications from the procedure through discharge (1-3 days), for peri-device leakage up to 90 days, and for late complications up to 30 days after discharge.
Compensation
Not stated in the trial record.
Follow-up
You would be followed for peri-procedural complications through discharge (1-3 days), for peri-device leakage up to 90 days after implant, and for late onset complications from discharge to 30 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06436924

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Completed
Not specifiedAges 18+Observational
Heart Rhythm Clinical and Research Solutions, LLC
~569 participants
Updated 2026-08-26 on ClinicalTrials.gov
What's tested:Left Atrial Appendage Device Implant

At a glance

Recruiting sites
0 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Peri-procedural complications
Measured over Procedure through discharge, an average of 1-3 days
+2 more outcomes measured
Atrial Fibrillation

NCT06436924

Where you'd take part

This study runs at 7 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Ascension St. Vincent

    Jacksonville, Floridano site contact published

  • Grandview Medical Center

    Birmingham, Alabamano site contact published

  • Medical University of South Carolina

    Columbia, South Carolinano site contact published

  • Memorial Health University Medical Center

    Savannah, Georgiano site contact published

  • Naples Community Hospital

    Naples, Floridano site contact published

  • Pima Heart and Vascular

    Tucson, Arizonano site contact published

  • The Medical Center of Aurora

    Aurora, Coloradono site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Saumil Oza, MD · PRINCIPAL_INVESTIGATOR · St. Vincent's

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Peri-procedural complicationsProcedure through discharge, an average of 1-3 days

    Incidence of peri-procedural complications summarized descriptively and compared to historical data

  • Peri-device leakageDate of implant up to 90 days

    Assessed by successful closure of the left atrial appendage defined by peri-device leakage of \<5mm. This will be identified at the post implant imaging.

  • Late onset complicationsDischarge to 30 days.

    Incidence of post procedure complications summarized descriptively and compared to historical data.