Atlantic Lipid Lowering Treatment Optimization Program for High Cholesterol

This study, called the Atlantic Lipid Lowering Treatment Optimization Program, is looking at a new way to help people with high cholesterol (hypercholesterolemia) manage their condition. It focuses on conditions like Familial Hypercholesterolemia and other types of high cholesterol. The study will use standard care but add special enhancements to reach high-risk patients early, including outreach and encouraging genetic testing. You might be able to join if you are between 18 and 120 years old and have high LDL-C (bad cholesterol) levels, a history of heart disease, or other specific risk factors. The main goal is to see if this approach can help lower and maintain your LDL-C below 100 mg/dL within 6 months. The current status of the study is unclear, but it plans to enroll 250 participants.

Study design
This is an interventional study that plans to enroll 250 participants. It will use a comprehensive outreach approach in conjunction with your primary care provider.
What's involved
The study involves screening for high LDL-C and evidence of familial hypertension. A study team member will reach out to inform you about the study and the consent process.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint for measuring LDL-C maintenance is at 6 months from enrollment in the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06439654

Atlantic Lipid Lowering Treatment Optimization Program

Recruiting
NAAges 18+InterventionalSupportive care
Atlantic Health System
~250 participants
Updated 2025-08-03 on ClinicalTrials.gov
What's tested:Supportive care

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportion of patients with LDL-C maintenance<100
Measured over 6 months from enrollment in study
Familial Hypercholesterolemia
Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia
Apolipoprotein B 100, Familial Defective
High Density Lipoprotein Deficiency
Low-Density-Lipoid-Type Hyperlipoproteinemia

NCT06439654

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Atlantic Medical Group

    Clark, New Jerseystudy coordinator listed

    Not yet recruiting

  • Atlantic Medical Group

    Springfield, New Jerseystudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Robert D Fishberg, MD · PRINCIPAL_INVESTIGATOR · Atlantic Health System

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Eligibility criteria

Inclusion

LDL-C ≥160 mg/dL
Untreated LDL-C ≥190 with family history of CAD
Prior MI and currently without optimized lipid-lowering therapy
Family history of CAD in first degree relative
Personal history of CAD
Untreated triglycerides \>500
Elevated Lp(a) and/or high calcium scores
Consenting individuals

Exclusion

Individuals who are pregnant
Individuals who are incarcerated
Individuals with a terminal illness
Individuals who do not consent
  • Proportion of patients with LDL-C maintenance<1006 months from enrollment in study

    LDL-C \<100 mg/dL after at least six months of therapy