This study aims to understand pediatric pulmonary vein stenosis (PVS), a narrowing of blood vessels connecting the lungs to the heart. Researchers believe high Wall Shear Stress (WSS), a force on vein walls, might contribute to PVS. This study will use Ferumoxytol, a contrast agent, with Cardiac Magnetic Resonance Imaging (FcMRI) to see if WSS can be measured in infants' pulmonary veins. If successful, this method could help identify infants at risk for PVS and guide treatment. You may be eligible if you are under 18, weigh over 3 kg, and are already having an FcMRI as part of your medical care for other reasons, with a structurally normal heart. The study is currently unclear on its recruitment status.

Study design

This is a single-center, feasibility study involving 20 participants. It is an interventional study, meaning participants will receive a specific intervention.

What's involved

Participants will undergo a cMRI with ferumoxytol as part of their clinical care. The primary measurement of Wall Shear Stress will be taken at 12 months.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome, Wall Shear Stress, will be measured at 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.