Blood Flow Restriction Training for People With Disabilities

This study is looking at whether a type of exercise called Blood Flow Restriction Training can help people with disabilities improve their strength and muscle size. Many people with disabilities find it hard to exercise, which can lead to other health problems. Blood Flow Restriction Training involves doing low-intensity exercises while a cuff restricts blood flow to the limb. Researchers want to see if this method can give similar benefits to harder exercise. You might be able to join if you are an adult (18 or older), speak English, and can do upper body exercises. The study will compare strength, arm size, and muscle thickness after 6 weeks between those who do Blood Flow Restriction Training and those who do regular low-intensity exercise.

Study design
This is an interventional study that will randomize 24 participants into two groups: one receiving Blood Flow Restriction Training and the other receiving no blood flow restriction training. The study status is currently unclear.
What's involved
Participants will complete low load resistance training exercises, either with or without blood flow restriction, for 6 weeks. Measurements of strength, arm circumference, and muscle thickness will be taken at the end of this period.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 weeks, which is when the primary endpoints are measured.

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NCT06441422

Blood Flow Restriction Training for People With Disabilities

Recruiting
NAAges 18+InterventionalTreatment
Medical College of Wisconsin
~24 participants
Updated 2026-05-01 on ClinicalTrials.gov
What's tested:Blood flow restriction trainingNo blood flow restriction training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Difference in strength between low load blood flow restriction resistance training and low load resistance training
Measured over 6 weeks
+2 more outcomes measured
Weakness, Muscle
1 sites across 1 states
Wisconsin1

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Eligibility criteria

Inclusion

Male or female
Age \> or = 18
English speaking
Able to understand and perform upper extremity exercises

Exclusion

Pregnant
Body mass index \>40 kg·m-2
Uncontrolled hypertension (\>150/90 mmHg)
Presence of neuromuscular junction and other muscle diseases
Myocardial infarction in the past 6 months
Unstable cardiovascular disease
History of an upper limb deep vein thrombosis
History of autonomic dysreflexia
Upper extremity fracture within the last 6 months
  • Difference in strength between low load blood flow restriction resistance training and low load resistance training6 weeks

    This outcome will measure the efficacy of low load blood flow restriction training (LLBFR) on muscle strength. The difference in muscle strength as measured by change in 1-repetition maximum weight in pounds will be compared in individuals training with LLBFR on their arm extensors and individuals training with low load resistance training (LLRT) on their arm extensors compared to their baseline.

  • Difference in arm circumference between low load blood flow restriction resistance training and low load resistance training6 weeks

    This outcome will measure the efficacy of low load blood flow restriction training (LLBFR) on arm circumference. The difference in arm circumference as measured by tape measure will be the change in centimeters in individuals training with LLBFR on their arm extensors compared to individuals training with low load resistance training (LLRT) on their arm extensors when compared to their respective baseline.

  • Difference in muscle thickness change between low load blood flow restriction resistance training and low load resistance training6 weeks

    This outcome will measure the efficacy of low load blood flow restriction training (LLBFR) on muscle thickness. The difference in muscle thickness as measured by ultrasound will be the change in centimeters in individuals training with LLBFR on their arm extensors compared to individuals training with low load resistance training (LLRT) on their arm extensors when compared to their respective baseline.