This study, called GEARS, is looking at how high-intensity stationary cycling, a type of aerobic exercise, might affect the progression of Parkinson's disease (PD). Researchers also want to understand if your genetics play a role in how well this exercise works. They will recruit 200 adults with PD (Hoehn and Yahr stage I-III) from Cleveland and Salt Lake City. You would exercise three times a week for 12 months at a community center. Success will be measured by changes in your Parkinson's symptoms using a scale called the MDS-UPDRS III. The study status is currently unclear.

Study design

This is an interventional study planning to enroll 200 participants. It will explore the effects of high-intensity stationary cycling.

What's involved

You would participate in community-based exercise sessions three times a week for 12 months. There will be five in-person assessments at Cleveland Clinic or the University of Utah over approximately 12.5 months.

Compensation

Not stated in the trial record.

Follow-up

Your Parkinson's symptoms will be measured at enrollment, 6 months, and 12 months post-enrollment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.