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PASS2 for Smoking Cessation and Pain in Veterans

This study, called PASS2, is looking at new ways to help Veterans who smoke and have ongoing (chronic) pain. It tests a program called PASS2, which combines telehealth counseling for quitting smoking with ways to manage pain. You'll also complete nightly surveys about your smoking, pain, and steps. This is compared to standard care, which is a referral to a VA smoking cessation clinic. The study wants to see if PASS2 helps Veterans quit smoking more effectively and reduces how much pain interferes with their daily lives. To join, you need to be a Veteran enrolled at VACHS, currently use tobacco, be willing to try and quit, and have significant chronic pain (a pain intensity score of 4 or higher for over 90 days). The main goal is to see how many people quit smoking after 10 months.

Study design
This is an interventional study comparing two approaches to help Veterans. It plans to enroll 220 participants.
What's involved
The PASS2 intervention includes a proactive telehealth program and nightly surveys. The study will measure cigarette abstinence rates at a 10-month follow-up.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed up for 10 months to measure cigarette smoking abstinence rates and pain interference.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06442514

Pain and Smoking Study 2

Not Yet Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~220 participants
Updated 2026-07-24 on ClinicalTrials.gov
What's tested:PASS2Treatment as Usual

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cigarette Smoking Abstinence Rates
Measured over 10-month follow-up

Conditions

Smoking
Pain
Smoking Cessation

Explore related trials

Chronic PainSmoking

Where it's being run

1 sites across 1 states
Connecticut1

Study leadership

  • Lori Anne Bastian, MD MPH · PRINCIPAL_INVESTIGATOR · VA Connecticut Healthcare System West Haven Campus, West Haven, CT

Who to contact

Lori A Bastian, MD MPH
[email protected]
(203) 932-5711 · ext. 3830
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

being an enrolled Veteran at VACHS
current tobacco use
willingness to make a quit attempt
significant chronic pain defined as \>/=4 on the pain intensity portion of the Brief Pain Inventory (BPI) for more than 90 days

Exclusion

active diagnosis of dementia or psychosis in medical record
severely impaired hearing or speech
lack of telephone access
enrollment in concurrent research study that might affect main outcomes of this study
terminal illness
non-English speaking
pregnancy
provider advising against exercise
planned surgeries
clinically significant depressive symptoms (\>10 PHQ-9)

What this trial measures

  • Cigarette Smoking Abstinence Rates10-month follow-up

    In keeping with the SNRT recommendations for measuring abstinence, the investigators will use prolonged abstinence as our main outcome. During the 10-month follow-ups, patients will be asked about prolonged abstinence, "In the past 6 months, have you smoked a cigarette, even a puff?"