This study is comparing two ways to guide surgery for glioblastoma, a type of brain cancer. One group of patients will have surgery guided by standard contrast-enhanced MRI. The other group will have surgery guided by a special type of MRI called pH weighted Chemical Exchange Saturation Transfer (CEST) MRI. The goal is to see if using pH weighted CEST MRI to guide surgery, which can detect tumor tissue not seen on standard MRI, improves how long patients live without their cancer growing (progression-free survival). You could be eligible if you are at least 18 years old and have a newly diagnosed glioblastoma. The study is currently unclear on its recruitment status and plans to enroll 60 participants.

Study design

This is an interventional study that will randomize 60 participants into two groups to compare different surgical guidance methods.

What's involved

You would undergo surgical resection, radiation therapy, and receive temozolomide. You would also have MRI scans during follow-up appointments.

Compensation

Not stated in the trial record.

Follow-up

After treatment, patients are followed up at 3, 6, 12, and 24 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.