iTBS for Posttraumatic Stress Disorder in Veterans

This study is looking at a treatment called intermittent theta burst stimulation (iTBS) for veterans with posttraumatic stress disorder (PTSD). iTBS is a type of transcranial magnetic stimulation (TMS) that uses magnetic pulses to stimulate parts of the brain. Researchers want to see if iTBS can help reduce PTSD symptoms. You might be able to join if you are a veteran between 18 and 80 years old, have a documented PTSD diagnosis with ongoing symptoms (PCL-5 score of 31 or higher), and are fluent in English. The main goal is to see how much your PTSD symptoms change right after treatment, using a measure called CAPS-5. The current status of this study is unclear.

Study design
This is a randomized study comparing active iTBS to a sham (inactive) iTBS, involving 64 participants. Participants will be assigned by chance to receive either the active or sham treatment.
What's involved
You would have an initial visit for assessments and brain scans, then 50 iTBS sessions over five days. After treatment, you'll repeat the initial tests, and have phone check-ins for six months.
Compensation
Not stated in the trial record.
Follow-up
Your symptom levels will be checked through phone calls one, three, and six months after treatment to see how long the benefits last.

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NCT06449326

Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms

Recruiting
NAAges 18–80InterventionalTreatment
University of New Mexico
~64 participants
Updated 2026-07-06 on ClinicalTrials.gov
What's tested:Active Intermittent theta burst stimulationSham Intermittent theta burst stimulation

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
CAPS-5
Measured over Immediate post-treatment visit
Posttraumatic Stress Disorder
2 sites across 1 states
New Mexico2

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Veterans will be enrolled in this study if they:

Exclusion

Veterans will be excluded from participation in this study if there is:
  • CAPS-5Immediate post-treatment visit

    Clinician Administered PTSD Scale-DSM 5 (range 0-80; higher scores = more symptoms)