CO-LEAD for Improved Communication and Medication Adherence in Lupus

This study is testing an intervention called CO-LEAD to help people with systemic lupus erythematosus (SLE) better manage their medication. CO-LEAD aims to improve how doctors and patients talk about medication and any challenges in taking it. The study will train doctors to use effective communication strategies, review your pharmacy refill information, and work with you to find solutions for any medication adherence problems. The goal is to see if these improved discussions lead to better medication use over time. You may be able to join if you are between 18 and 90 years old and have SLE. The study is currently unclear about its recruitment status.

Study design
This is an interventional study with a planned enrollment of 480 participants. The study does not specify if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The frequency of adherence discussions will be measured during the intervention period, which can last up to 2 years.

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NCT06458075

Intervention to Improve Communication and Medication Adherence in Lupus

Recruiting
NAAges 18–90InterventionalHealth services
Duke University
~480 participants
Updated 2026-08-17 on ClinicalTrials.gov
What's tested:CO-LEAD

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Frequency of adherence discussions
Measured over During intervention period (up to 2 years)
Systemic Lupus Erythematosus
1 sites across 1 states
North Carolina1
  • Kai Sun, MD · PRINCIPAL_INVESTIGATOR · Duke University

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Do you actually qualify for this trial?

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Eligibility criteria

Exclusion

Does not wish to be audio recorded
A minor without a parental/legal guardian and/or
Unable to give consent
  • Frequency of adherence discussionsDuring intervention period (up to 2 years)

    Proportion of SLE patient visits in which a nonjudgmental, patient-centered adherence discussion took place as determined by analysis of clinic visit audio recordings