Testing Intergenerational Suicide Risk in Mother-Child Pairs

This study is looking into how a mother's emotions might influence the risk of suicide in her children. It aims to understand if difficulties with emotion regulation (how we manage our feelings) in mothers can be passed down to their children, increasing their risk for suicidal thoughts and behaviors. The study will test two approaches: Dialectical Behavior Therapy Skills Group Training (a type of therapy that teaches coping skills) and Safety Planning Intervention (a plan to help manage suicidal crises). You might be able to join if you are a biological mother with legal custody of a child aged 9-11 and have a history of suicidal behavior. The study will measure child suicidal thoughts and behaviors over 24 months to see if these interventions are helpful. The current status of the study is unclear.

Study design
This is an interventional, randomized controlled trial planning to enroll 150 participants. Participants will be randomly assigned to receive either Dialectical Behavior Therapy Skills Training or treatment as usual.
What's involved
Participants will have a baseline assessment and four follow-up assessments over the next year. If selected for DBT skills training, it would occur once a week for 6 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 months after the initial assessment, with measurements taken at 3, 6, 12, and 24 months.

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NCT06463054

Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads

Recruiting
NAAll AgesInterventionalPrevention
University of Pittsburgh
~150 participants
Updated 2026-06-04 on ClinicalTrials.gov
What's tested:Dialectical Behavior Therapy Skills Group TrainingSafety Planning Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Child Suicidal Thoughts and Behaviors
Measured over Baseline, All Follow-up time points (3, 6, 12, and 24 months
+1 more outcome measured
Emotion Regulation
1 sites across 1 states
Pennsylvania1
  • Stephanie D Step, PhD · PRINCIPAL_INVESTIGATOR · University of Pittsburgh

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Eligibility criteria

Inclusion

Biological mothers with legal custody of target child between 9-11
Confirmed lifetime Biological mothers with legal custody of target child between 9-11
Confirmed lifetime history of suicidal behavior for mothers of suicidal behavior for mothers

Exclusion

Any mothers and children with major medical illnesses that might be associated with organic personality changes or ER difficulties (e.g. Parkinson's Disease, seizure disorders)
Cardiac nervous system abnormalities that would influence physiological readings
Previous DBT (Dialectical Behavior Therapy) in the last six months
  • Child Suicidal Thoughts and BehaviorsBaseline, All Follow-up time points (3, 6, 12, and 24 months

    Suicidal thoughts and behaviors will be assessed by the Columbia Suicide Severity Rating Scale (C-SSRS). C-SSRS will be scored with these domains, higher scores indicate worse outcomes Suicidal Ideation (Highest Level Endorsed 1-5) Intensity of Ideation (2-25) Suicidal Behavior (present during time period) Y/N Medical Damage for Attempt (0-5) Potential Lethality (if medical damage = 0) (0-2)

  • Child Suicidal Thoughts and BehaviorsBaseline, All Follow-up time points (3, 6, 12, and 24 months

    Suicidal thoughts and behaviors will be assessed the Intensity of Suicide Ideation Scale (SIS; PhenX Toolkit). Intensity of Ideation Subscale The sum ranges from 2 to 25, with the higher number indicating more intense ideation.