NCT06463249
Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions
Active, Not Recruiting
NAAges 18+InterventionalTreatmentSidney Kimmel Comprehensive Cancer Center at Johns HopkinsInvestigator-initiated
~200 participants
Updated 2026-07-20 on ClinicalTrials.gov
What's tested:CORE HelplineExtended HelplineEnhanced HelplineIntensive Helpline
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Weight (pounds) changes at 8 months from 2-month between Enhanced Helpline and Intensive Helpline arms
Measured over 8 months
Conditions
NCT06463249
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Johns Hopkins ProHealth
Baltimore, Marylandno site contact published
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Jessica Yeh, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
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Eligibility criteria
Inclusion
Women and men ages 18 or older
Able to complete all study requirements in English
Have been previously diagnosed with a malignant solid tumor, completed the required surgical, and/or chemotherapy and/or radiation curative intent therapy at least three months prior to enrollment, and have an anticipated treatment-free life span of 12 months or longer. Chemoprophylaxis with tamoxifen or aromatase inhibitors for breast cancer in women and anti- luteinizing hormone-releasing hormone (LHRH) therapy for prostate cancer in men will be permitted.
Have a BMI ≥ 27 kg/m2 (BMI ≥ 25 kg/m2 for Asians) and weight ≤ 400 lbs.
Have an email address for regular personal use
Have a smartphone for personal use, and are willing to use the phone to read emails and text messages, and use an app
Have adequate data plan and cell service to support daily use of weight loss app, receive text messages and to support coaching calls
Are willing to record weekly weights
Are willing to use a tracking app to log food and exercise daily
Are willing to complete coaching calls as planned
Are willing to prioritize weight loss efforts by making dietary changes and increasing physical activity
Exclusion
Received any chemotherapy (unless anti-hormonal therapy) and/or radiation three months or less prior to the proposed program date
Women who are breastfeeding, pregnant, or planning pregnancy within the next year
self-identification of uncontrolled concurrent medical condition likely to limit compliance with the program as determined by investigators.
current involvement in another organized weight loss program
current use of medications known to substantially affect body weight, including chronic oral steroids, Tirzepatide (Mounjaro™), and weight loss doses of other glucagon-like peptide 1 (GLP-1) agonists (e.g. Wegovy.)
bariatric surgery scheduled within the next 12 months
plan to move outside the continental United States in the next 12 months
Weight loss or gain of \>5.0% of body weight during 2 months prior to screening
What this trial measures
- Weight (pounds) changes at 8 months from 2-month between Enhanced Helpline and Intensive Helpline arms8 months
Weight change for Enhanced Helpline and Intensive Helpline in early non-responders