Microbiome Modulation for PTSD and Cirrhosis

This study is exploring if prebiotics (special fibers that feed good gut bacteria) can help people with both Post-Traumatic Stress Disorder (PTSD) and cirrhosis (a type of liver damage). Researchers are testing two dietary supplements: resistant potato starch (a prebiotic) and powdered cellulose (an active comparator, meaning it's used for comparison). You might be able to join if you are over 18, have a cirrhosis diagnosis, and can take oral medication. The main goal is to see if these supplements change the diversity of gut bacteria after 8 weeks. The current status of this study is unclear, and it plans to enroll 30 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 30 participants.
What's involved
You would need to be willing to comply with all study procedures, be available for the duration of the study, and provide study-related samples. You must also be able to take oral medication.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, gut microbiome alpha diversity, is measured at 8 weeks.

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NCT06464952

Microbiome Modulation With Prebiotics in PTSD and Cirrhosis

Recruiting
NAAges 18+InterventionalSupportive care
Hunter Holmes Mcguire Veteran Affairs Medical Center
~30 participants
Updated 2026-04-09 on ClinicalTrials.gov
What's tested:Resistant potato starchPowdered cellulose

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Gut microbiome Alpha Diversity between groups
Measured over 8 weeks
Cirrhosis
PTSD
1 sites across 1 states
Virginia1

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  • Gut microbiome Alpha Diversity between groups8 weeks

    Shannon diversity at end of interventions between both groups