Understanding Pain After Surgery

This observational study wants to understand how different personal factors, like your concerns about pain, sleep, and anxiety, affect your pain experience after surgery. Researchers are looking at how these factors, along with whether you receive regional anesthesia (numbing medication like an epidural or nerve block), impact your pain levels, how much opioid medication you use, and if you develop long-lasting pain after surgery. The main goal is to see if these personal factors change how well regional anesthesia works. They will measure your maximum pain score in the first 24 hours after surgery. This study is for adults aged 18 and older who speak English and are having surgery that requires a hospital stay. The study is currently unclear on its recruitment status and plans to include about 1000 people.

Study design
This is an observational study, meaning researchers will watch and collect information without giving you a specific treatment. About 1000 people are planned to be included.
What's involved
You would need to be willing to answer a survey about your feelings and potentially participate in an audio-recorded interview.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint measures pain over the first 24 hours after surgery.

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NCT06466941

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

Recruiting
Not specifiedAges 18+Observational
Brigham and Women's Hospital
~1,000 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:regional anesthesiano regional anesthesiaacute pain consultationno acute pain consultation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Maximum pain score over the first 24 hours after surgery
Measured over 0-24 hours
Acute Pain
Chronic Post Operative Pain
Opioid Use
1 sites across 1 states
Massachusetts1
  • Robert Edwards, PhD · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital

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Eligibility criteria

Inclusion

Age ≥ 18
English speaking
Surgical or procedural patient who will be admitted postoperatively
Willingness to answer psychosocial survey and/or audio recorded semi-structured interview

Exclusion

Cognitive dysfunction that precludes communication
  • Maximum pain score over the first 24 hours after surgery0-24 hours

    Maximum pain score (numerical pain rating score 0-10) over the first 24 hours after surgery