Speech Motor Learning and Retention Study
This study is looking at how the brain learns and remembers new speech movements. Researchers will use a device called continuous theta-burst stimulation (cTBS), which is a non-invasive way to stimulate the brain, along with an auditory adaptation task where you'll read sentences and hear your voice altered. The goal is to understand which brain areas are involved in learning and remembering speech. You might be able to join if you are a right-handed, fluent English speaker between 18 and 40 years old, have normal hearing, and no speech or reading disorders. The study will measure how well you learn new speech patterns at the end of a 30-minute session and how well you remember them 24 hours later. The current status of this study is unclear.
- Study design
- This is an interventional study planning to enroll 160 participants.
- What's involved
- You would participate in a 30-minute learning session and then a re-test session 24 hours later, which also lasts 30 minutes.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your learning will be re-tested 24 hours after the initial learning session.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Speech Motor Learning and Retention (Aim 1)
At a glance
Conditions
NCT06467305
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Yale Child Study Center
New Haven, Connecticutno site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- David Ostry · PRINCIPAL_INVESTIGATOR · Yale University
Who to contact
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Inclusion
Exclusion
What this trial measures
- Speech motor learningPerformance as measured at the end of learning (30 minute session)
Audapter software will be used to alter the first and second formant frequencies of the spoken words and this is played back to subjects through headphones. Subjects will be tested both with unaltered feedback and with abruptly introduced frequency shifts.The change in the first (F1) and second format frequency (F2) values will be assessed using Praat.
- Retention of learning24 hours after learning (re-test lasts 30 minutes)
The retention of adaptation to altered auditory feedback (and relearning) will be quantified in terms of F1 and F2 frequency shifts (relative to pre-training baseline). Larger values indicate more complete relearning or retention.