C-peptide for Hypoglycemia in Type 1 Diabetes
This study is looking at how a natural protein called C-peptide might help people with type 1 diabetes when their blood sugar gets too low (hypoglycemia). When blood sugar drops, the body usually releases a hormone called glucagon to raise it. However, in type 1 diabetes, this response can be weak. Researchers want to see if giving C-peptide during low blood sugar episodes can increase glucagon and help the body produce more sugar. You might be able to join if you are 18-40 years old, have a BMI (Body Mass Index) under 30, and do not smoke, are not pregnant, and don't have certain other health conditions like heart disease. The main goal is to measure glucagon levels during the procedure. The current status of the study is unclear, and it plans to enroll 38 participants.
- Study design
- This interventional study will involve healthy volunteers and people with type 1 diabetes. Participants will receive either C-peptide or a saline (saltwater) infusion during insulin-induced low blood sugar.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Glucagon levels will be measured during the procedure, up to 2.5 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Effect of C-peptide on Hypoglycemic Counterregulation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jason Winnick, PhD · PRINCIPAL_INVESTIGATOR · University of Cincinnati
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- GlucagonDuring procedure, up to 2.5 hours
from plasma