Test 2 Treat: Improving Cholesterol Management After a Heart Event

This study, called "Test 2 Treat," is looking at ways to improve how high cholesterol (LDL-C) is tested and treated in patients who have been hospitalized for a heart event like a heart attack (STEMI or NSTEMI) or a procedure to open blocked heart arteries (percutaneous coronary revascularization). Researchers want to see if educating doctors and patients, and having a "care champion" communicate with patients after they leave the hospital, can help more people reach their cholesterol goals. The care champion will encourage patients to stick to their cholesterol-lowering medication, get their cholesterol retested, and follow up with their doctor. The main goal is to see if these efforts lead to a better reduction in LDL-C levels within 6 to 8 months after leaving the hospital. You may be eligible if you are 18 or older, had a recent heart event, and have an LDL-C level of 70 mg/dL or higher during your hospital stay.

Study design
This interventional study plans to enroll 400 participants. It compares patients who receive support from a "care champion" to those who do not, to see if the care champion helps lower cholesterol.
What's involved
You will provide clinical data and patient-reported outcomes at baseline and 6 months. Your care champion will also record data related to their communication with you.
Compensation
Not stated in the trial record.
Follow-up
Your LDL-C levels will be tracked from your hospital admission up to 6 to 8 months after you are discharged.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06471036

Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?

Recruiting
NAAges 18+InterventionalPrevention
Duke University
~400 participants
Updated 2026-07-16 on ClinicalTrials.gov
What's tested:Care Champion Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Within-patient change in LDL-C (low-density lipoprotein cholesterol) from baseline (during admission) to last LDL-C level checked within 6+2 (8) months post-discharge
Measured over Baseline to 6+2 (8) months post-discharge
ASCVD
LDL-C
1 sites across 1 states
Minnesota1

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  • Within-patient change in LDL-C (low-density lipoprotein cholesterol) from baseline (during admission) to last LDL-C level checked within 6+2 (8) months post-dischargeBaseline to 6+2 (8) months post-discharge

    To test effectiveness of implementing a care champion intervention to help patients navigate the inpatient-to-outpatient transition after hospitalization for MI and/or percutaneous coronary revasc., in order to improve the achievement of LDL-C goals.