Vaginal Ecosystem and Network in the United States Study

This observational study, called the Vaginal Ecosystem and Network in the United States Study, is looking at how the balance of bacteria and other tiny organisms in the vagina (the vaginal microbiome) affects conditions like Bacterial Vaginosis, Candidiasis (yeast infections), and Urinary Tract Infections. Researchers will collect a vaginal swab from you to analyze the microbiome using special tests (PCR and NGS). The main goal is to understand how different microbiome patterns are linked to these conditions. The study aims to enroll 3250 healthy women, aged 18 to 89, who are not pregnant or trying to conceive. The study's success will be measured by analyzing the microbiome from your swab on the first day.

Study design
This is an observational study with a planned enrollment of 3250 participants. It involves collecting vaginal swab samples from healthy individuals and those with diagnosed gynecological conditions.
What's involved
You would provide a vaginal swab sample for analysis. The study does not specify additional visits or procedures.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, microbiome analysis, is measured at Day 1. No further follow-up is specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06472765

Vaginal Ecosystem and Network in the United States Study

Enrolling by Invitation
Not specifiedAges 18–89Observational
Vaginal Biome Science
~3,250 participants
Updated 2025-07-01 on ClinicalTrials.gov
What's tested:Vaginal Swab Collection

At a glance

Recruiting sites
0 of 21 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Microbiome Analysis
Measured over Day 1
Bacterial Vaginosis
Candidiasis
Urinary Tract Infections
Genitourinary Syndrome of Menopause
Lichen Sclerosus
Lichen Planus
Vulvodynia
Endometriosis
Ureaplasma Infections
Cancer
Desquamative Inflammatory Vaginitis

NCT06472765

Where you'd take part

This study runs at 21 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Amber Wellness Group

    Portland, Oregonno site contact published

  • Camel City Women's Wellness

    Winston-Salem, North Carolinano site contact published

  • Center for Pelvic Medicine

    Bryn Mawr, Pennsylvaniano site contact published

  • Center of the Health

    Corvallis, Oregonno site contact published

  • Claris Health

    Los Angeles, Californiano site contact published

  • Dr. Christina Enzmann at Easton Advanced Aesthetics and Regenerative Medicine

    Easton, Marylandno site contact published

  • Empire OBGYN

    Kenmore, New Yorkno site contact published

  • Empowered Midwifery and Wellness LLC

    Alexandria, Minnesotano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Kimberly Capone, PhD · PRINCIPAL_INVESTIGATOR · Vaginal Biome Science

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Healthy cis-gender women between ages 18 and 89

Exclusion

Pregnant or trying to conceive (i.e. IVF, IUI)
  • Microbiome AnalysisDay 1

    To analyze the vaginal microbiome in patients with diverse vaginal health conditions using next-generation sequencing (NGS) and a 56-panel PCR test to understand microbial diversity and implications for disease management.