NCT06475742

Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus

Enrolling by Invitation
PHASE3Ages 18–75InterventionalTreatment
Viatris Innovation GmbH
~680 participants
Updated 2026-07-28 on ClinicalTrials.gov
What's tested:Cenerimod

At a glance

Recruiting sites
0 of 122 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Treatment-emergent adverse events
Measured over Day 1 (post dose) to a maximum of 5.5 years
+2 more outcomes measured
Lupus Erythematosus, Systemic
122 sites across 30 states
Georgia11
Philippines10
Argentina8
Florida7
Colombia7
Poland7
Chile6
Greece6
  • Clinical Trials · STUDY_DIRECTOR · Viatris Innovation GmbH

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Completed the 12-month double-blind treatment period of either of the parent studies (ID-064A301, ID-064A302).
Did not meet any study treatment stopping criteria during the parent study.
Completed the last scheduled visit of the parent study. Participants who did not complete the last scheduled visit for reasons beyond their control may be eligible for this study upon approval by the sponsor. 3. Women of child-bearing potential:
Negative pregnancy test at Visit 1.
Agreement to undertake monthly urine pregnancy tests from Visit 2 up to 6 months after study treatment discontinuation.
Agreement to use a highly effective method of contraception from Visit 1 up to 6 months after study treatment discontinuation.
  • Treatment-emergent adverse eventsDay 1 (post dose) to a maximum of 5.5 years

    Occurrence of treatment-emergent adverse events up to the final study visit (maximum 5 years of study treatment plus 6-month safety follow-up period).

  • Serious adverse eventsDay 1 (post dose) to a maximum of 5.5 years

    Occurrence of serious adverse events up to the final study visit (maximum 5 years of study treatment plus 6-month safety follow-up period).

  • Adverse events of special interestDay 1 (post dose) to a maximum of 5.5 years

    Occurrence of adverse events of special interest up to the final study visit (maximum 5 years of study treatment plus 6-month safety follow-up period). Adverse events of special interest include the anticipated risks of treatment with cenerimod, known class effects, and events that may be related to systemic lupus erythematosus comorbidities, i.e., adverse events related to: * Effects on heart rate and rhythm * Hypotension * Hypertension * Cardiovascular * Hepatobiliary disorders / liver enzyme abnormalities * Pulmonary * Eye disorders * Infections * Skin malignancies * Non-skin malignancies