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NCT06476106

Human Research Program Flight Thigh Cuff

Enrolling by Invitation
NAAll AgesInterventionalSupportive care
National Aeronautics and Space Administration (NASA)
~10 participants
Updated 2025-04-01 on ClinicalTrials.gov
What's tested:Venoconstrictive Thigh Cuff (VTC)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Internal Jugular Vein (IJV) area
Measured over Thigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return
+3 more outcomes measured

Conditions

Healthy

Explore related trials

Healthy

Where it's being run

1 sites across 1 states
Texas1

Study leadership

  • Brandon R Macias, PhD · PRINCIPAL_INVESTIGATOR · National Aeronautics and Space Administration (NASA)

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Astronauts participating in missions that are ≥2 months

Exclusion

Having known allergies to proparacaine hydrochloride ophthalmic solution precludes participation in this study
Use of ethinyl estradiol Combined Oral Contraceptive (COC) pills precludes participation in this study
Having increased risk of venothromboembolism (VTE) based on preflight thrombosis/clotting related biomarkers precludes participation in this study

What this trial measures

  • Internal Jugular Vein (IJV) areaThigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return

    Measured using Ultrasound.

  • IJV pressureThigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return

    Measured using the VeinPres device during Ultrasound.

  • Intraocular Pressure (IOP)Thigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return

    Measured using the Pneumatonometer.

  • stroke volumeThigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return

    Measured from data collected during Ultrasound.