Improving Sleep in Veterans with Traumatic Brain Injury, PTSD, and Chronic Pain

This study is looking for Veterans who experience a combination of traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and chronic pain, often called the "polytrauma clinical triad." These conditions can lead to sleep problems and other difficulties. Researchers want to see if improving sleep can help with these interconnected issues. You might be asked to use a Morning Bright Light Therapy device or a Negative Ion Generator for 60 minutes each morning. The main goal is to measure how well you sleep using a wrist-worn device before and after four weeks of treatment. To join, you must be a Veteran, speak English, have phone and internet access, report current sleep disturbances, and have a documented history of TBI. You also need to be stable on any current treatments for depression, anxiety, sleep, or pain. The study is currently unclear on its recruitment status and plans to enroll 96 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 96 participants, but the phase of the study is not specified.
What's involved
Participants will sit in front of a device (either a lightbox or a negative ion generator) for 60 minutes every morning for four weeks. Sleep will be measured using a wrist-worn actigraphy device before and after this period.
Compensation
Not stated in the trial record.
Follow-up
Sleep efficiency will be measured at pre-treatment and post-4 weeks of treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06477796

Improving Sleep in Veterans With the Polytrauma Clinical Triad

Recruiting
NAAges 18–89InterventionalSupportive care
VA Office of Research and Development
~96 participants
Updated 2026-06-29 on ClinicalTrials.gov
What's tested:Morning Bright Light TherapyNegative Ion Generator

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Sleep Efficiency via wrist based actigraphy
Measured over Pre- and post-4 weeks of MBLT or sham treatment
Traumatic Brain Injury
Post-traumatic Stress Disorder
Chronic Pain
1 sites across 1 states
Oregon1
  • Jonathan E Elliott, PhD · PRINCIPAL_INVESTIGATOR · VA Portland Health Care System, Portland, OR

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Eligibility criteria

Inclusion

Veteran
English speaking with phone and internet access
Current self-reported sleep disturbances
Clinical stable for current pharmacologic or behavioral health treatments for depression, anxiety, sleep and pain
Documented history of TBI

Exclusion

Decisional impairment and/or dementia
Current usage of a lightbox or negative ion generator
Shift work
History of macular degeneration and/or bipolar disorder
Evidence for suicidal ideation
Cancer diagnosis within the past 6 months
Surgery within the past 6 months
Substance abuse within the past 6-12 months
Significant impairing post-stroke residual hemiparesis
  • Sleep Efficiency via wrist based actigraphyPre- and post-4 weeks of MBLT or sham treatment

    Sleep efficiency is defined by the total time asleep divided by total time spent in bed