This study is looking at whether carnosine, a natural food ingredient found in chicken and red meat, can help people with Peripheral Arterial Disease (PAD) walk better. PAD is a condition where narrowed arteries reduce blood flow to your limbs. Researchers want to see if taking 2 grams of carnosine daily for six months improves walking ability. You might be able to join if you are between 40 and 80 years old, can read English, and have a specific ankle-brachial index (ABI) measurement, which checks blood flow in your legs. The main way they will measure success is by how far you can walk in a six-minute test.

Study design

This is a double-blinded study, meaning neither you nor your doctors will know if you are receiving carnosine or a placebo. It plans to enroll 144 participants, divided equally into two groups.

What's involved

You would take carnosine or a placebo for six months. Researchers will measure your walking distance, blood flow, and take blood and urine samples before and after the treatment period.

Compensation

Not stated in the trial record.

Follow-up

After the six months of treatment, participants will be followed for an additional three months to see how long the effects of carnosine last.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.