Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

This study is looking at a new way to help people in the emergency department (ED) who are at risk for heart problems due to high cholesterol (lipid disorders). It's testing an intervention called EMERALD, which involves checking your cholesterol in the ED, calculating your risk for heart disease, prescribing a statin medication (rosuvastatin 10 or 40 mg daily), offering healthy lifestyle counseling, and connecting you with ongoing care. The goal is to see if this approach can lower your "bad" cholesterol (LDL-C) more effectively than usual care. You might be able to join if you are 40-75 years old, being evaluated for a heart attack in the ED, and have a certain risk for heart disease or a history of conditions like diabetes or stroke.

Study design
This is an interventional study planning to enroll 130 participants. Participants will be randomly assigned to receive either the EMERALD intervention or usual care.
What's involved
You would have your cholesterol checked in the ED and again at 30 days. You would also receive a statin medication, healthy lifestyle counseling, and a referral for ongoing care.
Compensation
Not stated in the trial record.
Follow-up
Your LDL-C will be measured at 30 days after your ED visit.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06488105

Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

Recruiting
PHASE2Ages 40–75InterventionalPrevention
Wake Forest University Health Sciences
~130 participants
Updated 2026-02-27 on ClinicalTrials.gov
What's tested:Statin (rosuvastatin 10 or 40 mg daily, depending on risk)Healthy Lifestyle CounselingOutpatient Followup

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percent change in low-density lipoprotein cholesterol (LDL-C) at 30 days
Measured over Index ED encounter through 30 days (-3, +11 days)
Lipid Disorder
Hypercholesterolemia
Cardiovascular Diseases
Atherosclerosis
1 sites across 1 states
North Carolina1

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  • Percent change in low-density lipoprotein cholesterol (LDL-C) at 30 daysIndex ED encounter through 30 days (-3, +11 days)

    Percent change in LDL-C from the index Emergency Department (ED) encounter through 30 days