Rehabilitation for Knee Arthritis in Veterans

This study is looking at ways to help Veterans with knee osteoarthritis (KOA), a common type of arthritis, maintain the improvements they get from physical therapy. Researchers are testing two approaches: Health Coaching and a Remote Incentive Program. The Remote Incentive Program uses games, social encouragement, and monitoring to help people stick with their exercises. The main goal is to see if these interventions help people keep up with exercise and physical activity for 6 to 18 months after physical therapy. You might be able to join if you are a Veteran aged 40-90, have knee osteoarthritis, and are starting physical therapy or just had your first session. The study is currently unclear about its recruitment status and plans to enroll 254 participants.

Study design
This is a randomized clinical trial with a factorial design, meaning participants will be randomly assigned to different groups to test the interventions. It plans to enroll 254 participants.
What's involved
Participants will interact with a clinical trial platform on their smartphone to capture important information. The study aims to measure outcomes between 6 and 18 months.
Compensation
Not stated in the trial record.
Follow-up
The study will measure outcomes between 6 and 18 months after the interventions.

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NCT06488144

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

Recruiting
PHASE3Ages 40–90InterventionalTreatment
VA Office of Research and Development
~254 participants
Updated 2026-01-08 on ClinicalTrials.gov
What's tested:Health coachRemote Incentive Program

At a glance

Recruiting sites
1 of 5 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
KOOS (Knee Osteoarthritis Outcome Score)
Measured over all available measures between 6-18 months (time-averaged effect)
Osteoarthritis, Knee
5 sites across 5 states
Alabama1
Nebraska1
Oregon1
Pennsylvania1
Washington1
  • Joshua F. Baker, MD MSCE · PRINCIPAL_INVESTIGATOR · Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Clinical diagnosis or chronic knee osteoarthritis.
Age between 40-90 years
Initiating physical therapy for KOA (has initial appointment within the next month or had first PT visit within the last 7 days)
To be randomized: PT feels that they are able to safely and reliably participate in ongoing exercise.
To be randomized: must have completed at least 4 virtual or in-person appointments with PT
To be randomized: must sync their Fitbit at least monthly.

Exclusion

Lack of a smart phone allowing interaction with the WTH platform
Inability to walk 2 blocks without assistance
Poorly controlled crystalline arthritis or other diagnosis of inflammatory arthritis.
Treating provider or LSI believes life-expectancy is \<1 year
Based on LSI or treating provider discretion: exclusions may occur for severe heart failure, unstable angina, end stage renal disease, severe chronic obstructive or other pulmonary disease, or other chronic illness felt to limit participants ability to participate in exercise or resulting in potential safety risk
Severe pain in a non-knee area limiting daily function
Non-English speakers or poor reading ability limiting ability to interact with text messages.
Pregnancy
Receiving physical therapy outside of the VA.
  • KOOS (Knee Osteoarthritis Outcome Score)all available measures between 6-18 months (time-averaged effect)

    The KOOS score is a validated and widely used measure of knee-related pain and physical functioning that has been validated in both knee injury and KOA populations. The KOOS measures symptoms and disability on five subscales: Pain, other Symptoms, Function in Activities of Daily Living, Function in Sports and Recreation, and Quality of Life (QOL). Range is from 0-100 for each subscale with lower scores suggesting worse patient experience.