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StableEyes for Dizziness in Multiple Sclerosis

This study is testing a new treatment called StableEyes for dizziness in people with multiple sclerosis (MS). StableEyes is a device that helps you do gaze stabilization exercises, which are designed to improve how your eyes stay focused when your head moves. The study wants to see if doing these exercises daily is better than doing them less often. We are looking for people aged 18 to 89 with a neurologist-confirmed diagnosis of MS, or healthy volunteers, who can speak and understand English. The main goal is to measure improvements in your composite VOR gain (cVOR gain), which is a way to check how well your eyes stay steady during head movements, over 18 weeks. The study is currently recruiting 138 participants.

Study design
This interventional study plans to enroll 138 participants. It aims to compare daily personalized gaze stabilization training with intermittent training.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your composite VOR gain will be measured at various points up to 18 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06495138

Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis

Recruiting
NAAges 18–89InterventionalTreatment
Emory University
~138 participants
Updated 2025-07-16 on ClinicalTrials.gov
What's tested:StableEyes

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Composite VOR gain (cVOR gain)
Measured over Weeks 0,1,2,3,4,5,6, 7, and 18

Conditions

Multiple Sclerosis

Explore related trials

DizzinessMultiple Sclerosis

Where it's being run

1 sites across 1 states
Georgia1

Study leadership

  • Colin Grove, PT, MS, DPT, PhD · PRINCIPAL_INVESTIGATOR · Emory University

Who to contact

Colin Grove, PT, DPT, MS, PhD
[email protected]
(404) 712-8685
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per The 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS, or a healthy volunteer without a diagnosis of multiple sclerosis or any related neurological conditions
Fluent in speaking and understanding English
Subjects with multiple sclerosis have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months

Exclusion

Clinically isolated syndrome or radiologically isolated syndrome.
Worsening MS symptoms during the prior 60 days
Immunotherapy change in the prior 60 days
Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 90 mmHg at rest
Static visual acuity with correction of worse than 1.0 logMAR
Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus}
Convergence insufficiency
Intra-nuclear ophthalmoplegia
Vestibular Migraine
Major orthopedic conditions that limit cervical spine range of motion or that alter walking
Self-reported current or potential for pregnancy during enrollment
Ongoing participation in vestibular rehabilitation for dizziness

What this trial measures

  • Composite VOR gain (cVOR gain)Weeks 0,1,2,3,4,5,6, 7, and 18

    The team will conduct the video head impulse test (vHIT), a physiologic assay of vestibular semicircular canal pathway function. Angular vestibulo-ocular reflex gain will be calculated as eye velocity / head velocity during self-generated and/or passive high frequency head rotations which will be conducted in the yaw, pitch, roll, and/or semicircular canal planes.