Prebiotics for Ulcerative Colitis
This study is looking at how prebiotics, a type of dietary supplement, might affect the gut health and microbiome (the community of tiny organisms in your gut) in people with ulcerative colitis (UC) or Crohn's disease. Researchers believe that diet, especially plant-based foods, can improve the gut microbiome, which may impact inflammatory bowel disease (IBD) outcomes. You might be able to join if you are 18 to 85 years old, have biopsy-proven UC, and are experiencing active symptoms. The study will measure if taking a daily prebiotic supplement for 8 weeks can lead to clinical remission (a period where symptoms are reduced or absent), changes in a marker of inflammation called fecal calprotectin, and changes in your gut's microbial composition. The current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 70 participants. You will be randomly assigned to take a prebiotic supplement for 8 weeks, either starting at week 0 or week 8.
- What's involved
- You will take a daily prebiotic supplement for 8 weeks. Stool samples will be collected at weeks 0 and 8, and your dietary composition will be assessed at baseline and over 16 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Clinical remission, fecal calprotectin, and microbial composition will be measured at Week 8.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Impact of Prebiotics in Ulcerative Colitis
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Clinical remissionWeek 8
Clinical remission will be defined as a Simple Colitis Clinical Activity Index (SCCAI) \< 4. Range of SCCAI is 0-20 (higher is more severe).
- Change in fecal calprotectinWeek 8
Fecal calprotectin is a stool test that measures intestinal inflammation
- Microbial compositionWeek 8
Microbial composition includes a measurement and characterization of the relative quantity of genera and species.