Study on Oral Nicotine Products: Flavors and Nicotine Strength

This study is looking into how different flavors (sweet versus cool) and nicotine strengths (low versus high) in oral nicotine products (ONPs) affect young adults who currently use e-cigarettes. Researchers want to understand what makes these products appealing and how likely they are to be used frequently. The study aims to enroll 320 participants, aged 21 to 25, who exclusively use e-cigarettes and have never used other oral nicotine products. Success will be measured by how appealing participants rate the products and how much of the product they consume immediately after trying it. The current status of this study is unclear.

Study design
This interventional study plans to enroll 320 participants to compare different flavors and nicotine concentrations in oral nicotine products.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Product appeal and consumption will be measured immediately after the intervention.

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NCT06506162

Abuse Liability and Appeal of Oral Nicotine Products

Recruiting
NAAges 21–25InterventionalPrevention
University of Southern California
~320 participants
Updated 2026-07-09 on ClinicalTrials.gov
What's tested:FlavorNicotine concentration

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Product appeal ratings
Measured over immediately after the intervention
+1 more outcome measured
Nicotine Dependence
2 sites across 1 states
California2
  • John R Monterosso, PhD · PRINCIPAL_INVESTIGATOR · University of Southern California

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  • Product appeal ratingsimmediately after the intervention

    Participants will rate the sensory appeal of products and their motivation to use the products

  • Product consumptionimmediately after the intervention

    Participants will have periods in which ad lib use of the product ("use as much or as little as you like") and the total used will be recorded