International CRDS Registry for Calcium Release Deficiency Syndrome
This study is an international registry for Calcium Release Deficiency Syndrome (CRDS), a recently discovered genetic heart condition that can cause life-threatening irregular heartbeats (arrhythmias). Researchers want to learn more about CRDS, including how it affects people, how to best assess risk, and the most effective treatments. You may be able to join if you have a specific genetic change (RYR2 variant) that is known to cause CRDS, or a certain type of RYR2 genetic change. The main goal is to track how many people with CRDS experience a serious irregular heartbeat (Malignant Ventricular Arrhythmia) over five years. The current status of this study is unclear.
- Study design
- This is an observational study, meaning researchers will collect information without giving any specific treatments. It aims to enroll 500 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for five years to track the occurrence of Malignant Ventricular Arrhythmia.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
International CRDS Registry
At a glance
Conditions
Where it's being run
20 sites across 16 statesStudy leadership
- Thomas M Roston, MD, PhD · STUDY_CHAIR · University of British Columbia
- Jason D Roberts, MD MAS · PRINCIPAL_INVESTIGATOR · McMaster University
- SR Wayne Chen, PhD · PRINCIPAL_INVESTIGATOR · University of Calgary
Who to contact
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What this trial measures
- Malignant Ventricular Arrhythmia5 years
Composite of malignant syncope, ICD shock, cardiac arrest, and sudden cardiac death