Integrated Care for Opioid/Stimulant Use Disorder and Infections

This study is testing a new approach called the Integrated Infectious Diseases and Substance Use Disorder Clinic (IC). This clinic combines care for infections and treatment for opioid or stimulant use disorder into a single appointment, which can be in person or through telemedicine. The goal is to see if this integrated care can reduce the number of times people are re-hospitalized for infections after being discharged. You might be able to join if you are 18 or older, have been hospitalized for an infection related to injecting opioids or stimulants in the past 90 days, and are currently in the hospital for a related infection. The study will measure how many times people are re-hospitalized for infections within 6 months after leaving the hospital. The current recruitment status is unclear.

Study design
This is a randomized controlled trial involving two groups, comparing the Integrated Infectious Diseases and Substance Use Disorder Clinic (IC) to usual care. About 304 participants will be enrolled across five hospitals.
What's involved
If you join, you would have at least monthly appointments for 6 months at the Integrated Infectious Diseases and Substance Use Disorder Clinic (IC), either in person or via telemedicine.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after discharge from the hospital.

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NCT06513156

Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use

Recruiting
NAAges 18+InterventionalTreatment
Elana Rosenthal
~304 participants
Updated 2025-10-31 on ClinicalTrials.gov
What's tested:Integrated Infectious Diseases and Substance Use Disorder Clinic (IC)

At a glance

Recruiting sites
4 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Infection Rehospitalization
Measured over 6 months after discharge for index hospitalization
Opioid Use Disorder
Injection Related Infections
Stimulant Use Disorder
4 sites across 4 states
District of Columbia1
Georgia1
Maryland1
West Virginia1
  • Elana Rosenthal, MD · PRINCIPAL_INVESTIGATOR · University of Maryland, Baltimore

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Non-vertebral osteomyelitis
Vertebral osteomyelitis or discitis
Epidural, subdural, or extradural abscess
Intracranial or intraspinal abscess
Native joint septic arthritis
Prosthetic joint septic arthritis
Blood stream infection (bacterial or fungal)
Native valve Endocarditis
Prosthetic valve endocarditis
Cardiac Implantable electronic device infection
Infectious pseudoaneurysm and aneurysm
Infected vascular graft
Septic venous thrombosis
Skin and Soft tissue infection (cellulitis, skin abscess, necrotizing fasciitis)
Infected skin ulcer
Orthopedic hardware infection
Muscle abscess/myositis
Central nervous system infection (bacterial or fungal)
Bacterial or fungal ophthalmologic infection
Other abscess
Pulmonary septic emboli
Other acute bacterial or fungal infection deemed appropriate by site study team

Exclusion

1\. Infection due to a cause other than injection drug use, per determination of a site PI.
  • Infection Rehospitalization6 months after discharge for index hospitalization

    New hospitalization due to infection following discharge for index hospitalization