Predicting Postpartum Hemorrhage Risk
This study is testing a new way to predict postpartum hemorrhage (PPH), which is heavy bleeding after childbirth. Currently, risk assessments are basic. This research will use a "Novel PPH Risk Prediction Model" that automatically calculates your risk based on 21 factors. If you are in the intervention group, your care team will also receive a "Best Practice Advisory" with recommended actions if your risk is high. The study wants to see if using this model improves outcomes for mothers. You can join if you are delivering at Vanderbilt University Medical Center. Researchers will look at your health at discharge and 30 days after delivery to see if the new model helps.
- Study design
- This is an interventional, randomized controlled trial planning to enroll 12,500 women. It compares standard care with standard care plus a new risk prediction model.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your health will be followed until you leave the hospital (usually 2-4 days after delivery) and again at 30 days postpartum.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Pragmatic Randomized Controlled Trial to Predict Postpartum Hemorrhage
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Holly Ende, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Numerical hierarchical composite score of postpartum morbidity and mortality at hospital dischargeDate of randomization to Postpartum hospital discharge (usually 2-4 days)
Patients will be assigned the most severe morbidity and mortality outcome score based on a range of criteria from 1 to 7 with 1 being the least severe and 7 being the most severe outcome. 1 is Estimated blood loss \<1000 mL, 2 is Estimated blood loss \>=1000 mL, 3 is Mechanical treatment of hemorrhage (uterine tamponade device insertion, uterine compression suture), 4 is Post-delivery red blood cell transfusion, 5 is Uterine artery embolization, 6 is Hysterectomy due to bleeding, and 7 is Death. For example, a patient who experiences an estimated blood loss \>=1000mL and does not experience another more serious outcome would receive a score of 2, whereas a patient who requires a hysterectomy due to bleeding might meet several of the criteria, but would receive a score of 6, as this is the most severe criteria they experience.
- Numerical hierarchical composite score of postpartum morbidity and mortality at 30 days postpartum30 days postpartum
Patients will be assigned the most severe morbidity and mortality outcome score based on a range of criteria from 1 to 7 with 1 being the least severe and 7 being the most severe outcome. 1 is Estimated blood loss \<1000 mL, 2 is Estimated blood loss \>=1000 mL, 3 is Mechanical treatment of hemorrhage (uterine tamponade device insertion, uterine compression suture), 4 is Post-delivery red blood cell transfusion, 5 is Uterine artery embolization, 6 is Hysterectomy due to bleeding, and 7 is Death. For example, a patient who experiences an estimated blood loss \>=1000mL and does not experience another more serious outcome would receive a score of 2, whereas a patient who requires a hysterectomy due to bleeding might meet several of the criteria, but would receive a score of 6, as this is the most severe criteria they experience.