PLIA for Pain After PAO Surgery
This study is looking at whether a local anesthetic (pain-numbing medicine) called peri-incisional local infiltrative anesthesia (PLIA) can reduce pain after periacetabular osteotomy (PAO) surgery for hip dysplasia. PLIA is a combination of ropivacaine, epinephrine, ketorolac, and saline. Researchers want to see if PLIA helps with pain and reduces the amount of pain medication you need after surgery, and if the timing of when PLIA is given makes a difference. You could be eligible if you are 13 to 50 years old, have hip dysplasia, and are having PAO surgery at the University of Iowa Hospital and Clinics. The study is currently unclear on its recruitment status, but plans to enroll 120 participants. Success would mean patients experience less pain and use fewer pain medications after surgery.
- Study design
- This is an interventional study where participants will be randomly assigned to one of three groups: no PLIA, PLIA after incision closure, or PLIA during surgery. Participants will not know which group they are in (blinded).
- What's involved
- You will complete surveys at a preoperative appointment. All other information will be gathered from your medical chart.
- Compensation
- Not stated in the trial record.
- Follow-up
- Pain and pain medication usage will be measured from the Post Anesthesia Care Unit (PACU) until hospital discharge, an average of 3 days. You can ask about your study group at your 3-month follow-up visit.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
At a glance
Conditions
NCT06519955
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Iowa Health Care
Iowa City, Iowastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Post-operative pain after periacetabular osteotomy.Post Anesthesia Care Unit (PACU), 24 hours post op
Severity of pain will be measured by collection of the visual analog scale (VAS) for pain. Scale of 1-10.
- Pain medication usage after periacetabular osteotomy.Post Anesthesia Care Unit (PACU) to end of hospital stay, an average of 3 days.
The amount of pain medications taken will be measured using morphine equivalent dosing (MED).
- The impact of timing of PLIA administration on post-operative pain.Post Anesthesia Care Unit (PACU) to end of hospital stay, an average of 3 days.
The mean VAS pain will be compared between the different study groups. Scale of 1-10.
- The impact of timing of PLIA administration on MED.Post Anesthesia Care Unit (PACU) to end of hospital stay, an average of 3 days.
The mean MED will be compared between the different study groups.