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Online Pivotal Response Treatment Training in Autism Spectrum Disorder

This study is looking at an online training course called Pivotal Response Treatment Online (PRT-O) for parents of young children with Autism Spectrum Disorder (ASD). The goal is to see if parents can learn to effectively use PRT, a type of behavioral therapy, after taking the online course. Researchers will measure how well parents use PRT and if their children's functional verbal communication improves after 6 and 12 weeks. Children between 2 and 5 years old with an ASD diagnosis or strong suspicion of ASD can participate. The study aims to enroll 44 participants, but its current status is unclear.

Study design
This is an interventional study that plans to enroll 44 participants. It is testing a behavioral intervention, the Pivotal Response Treatment Online (PRT-O) Course.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in parent PRT implementation and child verbal utterances at 6 and 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06523387

Online Pivotal Response Treatment Training in Autism Spectrum Disorder

Recruiting
NAAges 2–5InterventionalTreatment
Stanford University
~44 participants
Updated 2026-05-19 on ClinicalTrials.gov
What's tested:Pivotal Response Treatment Online (PRT-O) Course

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline on Parent Fidelity of Pivotal Response Treatment Implementation as measured on the Home Video Observation (HVO)
Measured over 6 Weeks and 12 Weeks
+1 more outcome measured

Conditions

Autism Spectrum Disorder
Autism

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NCT06523387

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Stanford University

    Stanford, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Grace Gengoux, PhD · PRINCIPAL_INVESTIGATOR · Stanford University

Who to contact

Jane Huang
[email protected]
(650) 736-1235
Email the study team

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Eligibility criteria

Inclusion

2:0 to 5:11 years at the time of consent,
diagnosed with ASD (based on history, review of available medical records including diagnostic testing, e.g., Autism Diagnostic Observation Schedule) or suspicion of Autism Spectrum Disorder diagnosis, and confirmed with Autism Diagnostic Interview-Revised (ADI-R),
with significant adaptive communication deficits (i.e., either a Vineland-3 Communication subscale 2 Standard Deviations below average for 2 and 3 year olds and 3 Standard Deviations below for 4 and 5 year olds or a Vineland-3 Expressive V-scale Score 2 Standard Deviations below average for 2 and 3 year olds, or 3 Standard Deviations below for 4 and 5 year old, and at least moderate severity on the Clinical Global Impressions Severity (CGI-S) language subscale),
an English-speaking parent able to consistently participate in study procedures and conduct treatment in English,
stable psychotropic medication(s) or biomedical intervention(s) for at least 1 month prior to baseline measurements with no anticipated changes during study participation,
stable treatment (ABA, Floortime, or other interventions), speech therapy, and school placement for at least 1 month prior to baseline measurements with no expected changes during study participation,
no more than 60 minutes of 1:1 speech therapy per week

Exclusion

Children who have a primary language other than English
parent or child diagnosed with severe psychiatric disorder or unstable medical problem
previous adequate trial of pivotal response treatment resulting in parent meeting Pivotal Response Treatment fidelity of implementation at baseline
Receiving more than 15 hours of in home 1:1 ABA per week
living within 100 miles of Stanford University.

What this trial measures

  • Change from Baseline on Parent Fidelity of Pivotal Response Treatment Implementation as measured on the Home Video Observation (HVO)6 Weeks and 12 Weeks

    Parent Fidelity of Pivotal Response Treatment Implementation will be rated from 10 min HVO by trained coders naïve to treatment assignment and timepoint using established operational definitions from prior PRT studies (e.g., Hardan et al., 2015; Gengoux et al., 2019).

  • Change from Baseline on Child Functional Verbal Utterances as measures on the Home Video Observation (HVO)6 Weeks and 12 Weeks

    Child Functional Verbal Utterances will be rated from 10 min HVO by trained coders naïve to treatment assignment and timepoint using established operational definitions from prior PRT studies (e.g., Hardan et al., 2015; Gengoux et al., 2019).