Study Comparing Two Types of Electroconvulsive Therapy for Suicidal Thoughts
This study is looking at two different ways to deliver Electroconvulsive Therapy (ECT) for people experiencing suicidal thoughts, especially those with Major Depressive Disorder, Schizoaffective Disorder, or Bipolar Disorder. We are comparing a new approach called Sigma-Stim, which uses a lower electrical current (600mA or 700mA), to the standard Ultra-Brief Right Unilateral ECT (800mA). The main goal is to see if Sigma-Stim can reduce suicidal thoughts more effectively and with fewer memory side effects than the standard treatment. We expect to enroll about 30 participants who are already considered candidates for ECT by their doctors. The study will measure changes in suicidal thoughts through self-reports and clinician ratings over about four weeks.
- Study design
- This is a randomized clinical trial comparing two types of ECT in about 30 participants. Participants will be assigned to receive either Sigma-Stim or standard Ultra-Brief Right Unilateral ECT.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Suicidal thoughts will be measured through study completion, which is an average of four weeks.
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Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Nagy A Youssef, MD, PhD · PRINCIPAL_INVESTIGATOR · Pine Rest Christian Mental Health Services & Michigan State University
Who to contact
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What this trial measures
- Suicide Ideation - Self ReportThrough study completion, an average of four weeks
Beck Scale for Suicide Ideation (SSI-Worst and SSI-Current) - self reported. Minimum score of 0, maximum score of 42. Lower score indicates a better outcome.
- Suicide Ideation - Clinician RatedThrough study completion, an average of four weeks
Columbia Suicide Severity Rating Scale (C-SSRS) - clinician administered. Intensity of suicidal ideation: minimum score of 0, maximum score of 5. Lower score indicates a better outcome. Suicidal behavior not rated on a scale.