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NCT06529042

SCRIPT: Sickle Cell Risk in Pregnancy Tool

Enrolling by Invitation
Not specifiedAges 16–60Observational
Mount Sinai Hospital, Canada
~1,000 participants
Updated 2024-11-27 on ClinicalTrials.gov
What's tested:Non-Interventional

At a glance

Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Presence of Adverse Pregnancy Outcome
Measured over During pregnancy (until delivery of infant, up to 42 weeks of gestation)

Conditions

Sickle Cell Disease
Pregnancy, High Risk
Pregnancy Complications

Explore related trials

PregnancySickle Cell DiseaseHemoglobin

Where it's being run

3 sites across 3 states
Maryland1
British Columbia1
Quebec1

Study leadership

  • A. Kinga Malinowski, MD, MSc · PRINCIPAL_INVESTIGATOR · MOUNT SINAI HOSPITAL

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age \>16 years
HbSS, HbSC, HbS/β0-thalassemia, HbS/β+-thalassemia confirmed on Hb electrophoresis, high performance liquid chromatography, capillary electrophoresis, or genetic testing
Records of pregnancy care and birth at a participating centre
Pregnancy continuing to at least 16+0 weeks' gestation (41,42)

Exclusion

Inability to confirm SCD genotype
Incomplete medical records.

What this trial measures

  • Presence of Adverse Pregnancy OutcomeDuring pregnancy (until delivery of infant, up to 42 weeks of gestation)

    Yes, if any of the following events first noted during the pregnancy within the study period: acute anemia (yes, no), cardiac complication (yes, no), pulmonary complication (yes, no), hepatobiliary complication (yes, no), MSK complication (yes, no), splenic complication (yes, no), neurologic complication (yes, no), renal complication (yes, no); multi-organ failure (yes, no), venous thromboembolism (yes, no), vaso-occlusive event with admission (yes, no), red cell transfusion (yes, no), maternal mortality (yes, no), hypertensive disorder of pregnancy (yes, no), preterm birth (yes, no), small for gestational age (yes, no), or perinatal mortality (yes, no); defined based on published classifications.