The MOVE (Molecular Optimization Via Exercise) study is looking at characteristics of muscle, blood, and urine samples from older adults, aged 65-80. This study aims to understand how muscle cells age by comparing healthy adults who are either very active or mostly sedentary. Researchers will collect samples and perform physical and cognitive tests. The main goal is to look at muscle cellular aging using special techniques called spatial transcriptomics and single cell transcriptomics, measured on Day 2 of the study. This is an observational study, meaning there are no interventions or treatments being tested. The study is currently recruiting 80 participants.

Study design

This is an observational study involving 80 participants, split evenly by gender across different activity levels.

What's involved

You would have 3 study visits within 12 weeks, including physical assessments, exercise tests, cognitive tests, and collection of blood, urine, and a thigh muscle sample.

Compensation

Not stated in the trial record.

Follow-up

Optional follow-up visits may be completed at 12 and 24 months after the main study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.