Observational Study for Subjective Cognitive Decline or Mild Cognitive Impairment
This study is looking for adults aged 50 and older who have been diagnosed with subjective cognitive decline (SCD), meaning they notice changes in their memory or thinking, or mild cognitive impairment (MCI), which is a slight but noticeable decline in mental abilities. The goal is to understand how these conditions progress over time in people from under-resourced or underrepresented communities. Researchers will collect information from your medical records, including clinical diagnoses, test scores, and imaging. You will also have neuropsychological assessments (tests of thinking and memory) and fill out questionnaires. The study aims to follow 1000 participants for up to 5 years to learn more about the clinical presentation and course of these conditions.
- Study design
- This is an observational study, meaning participants will be followed over time without receiving any specific treatment from the study. It plans to enroll 1000 participants.
- What's involved
- You would participate in annual research visits for up to 5 years. These visits involve neuropsychological tests, behavioral questionnaires, and functional assessments. Information from your medical records, including neuroimaging and biofluid samples, will also be collected.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for up to 5 years to collect clinical data, neuropsychology, neuroimaging, and biofluids.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog
At a glance
Conditions
NCT06542458
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
The Ohio State University
Columbus, Ohiono site contact published
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI) at risk for dementia from under-resourced/underrepresented communities that we longitudinally collect clinical data, neuropsychology, neuroimaging, and biofluids5 years
This study is a longitudinal collection of clinical data, neuroimaging, neuropsychological assessments, and biofluids to establish a cohort of older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI) at risk for dementia from under-resourced/underrepresented communities from which hypotheses can be generated. Analysis will also include comparing the subject's longitudinal change over time data. Data will be analyzed with one way and repeated measures (ANOVAs) that will control for important covariates. All imaging data will be analyzed using qualitative visual interpretation and quantitative region of interest approach.