Harm Reduction for Smokers with Mental Illness Study
This study is looking at ways to help people with mental illnesses who smoke reduce the harm from cigarettes, especially if they aren't ready to quit completely. It compares providing e-cigarettes (NJOY) alone with providing e-cigarettes along with behavioral support called SWITCH IT. SWITCH IT involves coaching sessions and opportunities to explore e-cigarette options. The study aims to see if these approaches can reduce how much you smoke and how much nicotine your body takes in. You might be able to join if you are 21 or older, speak English, smoke at least 10 cigarettes a day, and have a diagnosis like schizophrenia, bipolar disorder, major depressive disorder, or anxiety disorders. The study is currently unclear about its recruitment status and plans to enroll 250 participants.
- Study design
- This interventional study plans to enroll 250 participants. It compares two groups: one receiving e-cigarettes only, and another receiving e-cigarettes with behavioral support.
- What's involved
- Participants will receive e-cigarettes for the first 8 weeks. Those in the SWITCH IT group will also have 7-10 behavioral support sessions over the first 8 weeks, with optional field trips in week 4.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your urine NNAL and CO levels will be measured at 8 weeks and 26 weeks. Self-reported cigarette use will be measured at 8 weeks and 16 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Harm Reduction for Smokers With Mental Illness
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Sarah I. Pratt, PhD · PRINCIPAL_INVESTIGATOR · Dartmouth Health
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in Urine NNALbaseline to 8 weeks, 8 weeks to 26 weeeks
urine levels of NNAL
- Change in CO levelbaseline to 8 weeks, 8 weeks to 26 weeks
carbon monixide level less than 6
- Change in self-reported cigarette usebaseline to 8 weeks 8 weeks to 16 weeks
self-report of combustible cigarette use