Balance Control and Recovery in Diabetic Peripheral Neuropathy
This study is looking at how diabetic peripheral neuropathy (DPN), a common condition affecting nerves in people with diabetes, impacts your balance. Researchers want to understand how DPN affects your ability to control your balance and recover from losing it, especially during everyday movements like sitting down, standing up, and when your balance is challenged. You might be able to join if you are 50 to 99 years old and have Type II diabetes with peripheral neuropathy. The study will measure your balance using special equipment and look at your muscle activity. The goal is to better understand how DPN contributes to falls and feelings of instability. The current status of this study is unclear.
- Study design
- This interventional study plans to enroll 60 participants aged 50 to 99 years old. It will compare balance and muscle activity in people with and without diabetic peripheral neuropathy.
- What's involved
- You will have your body measurements taken, sensation tested, and sensors placed on your leg muscles. You will then perform sit-to-stand and stand-to-sit movements, and stand on a treadmill while holding a ruler.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for primary endpoints will be taken at the first session, immediately after the interventions.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Balance Control and Recovery in Diabetes Peripheral Neuropathy
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Center of pressure using force plateFirst session (immediately after intervention)
Center-of-pressure sway will be assessed between groups. As participants sit down or stand up from a chair on the force plates, the ground reaction force will be collected. Then, using a mathematical approach, an ellipse will be fitted to the data to calculate the sway area. A higher sway area indicates an impairment during balance control.
- Center of mass using Vicon cameras.First session (immediately after intervention)
Center-of-mass sway volume will be assessed as the participant will walk in front of a high-speed camera, which will be recorded using the retroreflective markers. Then, a mathematical approach will be used to fit an ellipsoid to the data samples for each group. Higher sway volume means impairment in balance.
- Joint moment using Nexus softwareFirst session (immediately after intervention)
Joint moments will be assessed between groups using Vicon and force plates. This variable will be obtained using Nexus software, which combines both the inputs from Vicon and force plates.
- Local dynamic stability using Motek and Vicon systemFirst session (immediately after intervention)
Local dynamic stability will be assessed using the Motek treadmill and Vicon cameras. The Motek treadmill will provide the left and right perturbation, and the Vicon system will collect the kinematic data. Then, the MATLAB code will calculate local dynamic stability to identify impairment in balance recovery.